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Sci 33 (4), 459464 (2003)
Extracellular signal-regulated kinase and phosphoinositol-3 kinase mediate IGF-1 induced proliferation of fetal sheep cardiomyocytes
Neither compound affects FSH, LH, PRL, or TSH, providing genuine selectivity for the GH axis
The original Ipamorelin publication (Raun et al.) describes the pentapeptide molecule as "the first selective GH-secretagogue" with confirmed GH-releasing effects in animal and in vitro models without significant effects on ACTH, cortisol or prolactin
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