In a randomized, placebo-controlled intervention study with more than 900 older participants experiencing psychological distress, daily supplementation with folic acid (400 g) and vitamin B 12 (100 g) for two years did not reduce the occurrence of symptoms of depression despite significantly improving blood folate, vitamin B 12 , and homocysteine levels compared to placebo (109)
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If someone already has a vitamin B12 deficiency, then utilizing a vitamin B12 injection can help lift their mood
In addition, B12 deficiency can result in Megaloblastic Anemia, a type of anemia in which the red blood cells grow without dividing, becoming enlarged
Regular check-ups are important to make sure your B12 therapy is working right