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4.1 Skin Biopsy Skin biopsies have emerged as an adjuvant and diagnostic tool for diabetic neuropathy, particularly for small-fiber involvement, offering distinct advantages and limitations compared with other methods

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Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation

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BPC-157s ability to improve blood flow and angiogenesis supports the damaged tissue by delivering nutrients more efficiently