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Other studies show that Cotaduide could intervene and reverse NASH through improving metabolism in the liver including lipid and glucose metabolism via GCGR in mice, suggesting that Cotaduide may be a potential and viable therapeutic as a targeted drug intervention to reverse disease progression of NASH (131)
Neurotoxicology 92:166179
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In addition to its biosynthesis, L-carnitine can also be obtained from the diet, where in the gut L-carnitine can either be directly absorbed or converted to GBB or crotonobetaine by bacteria residing in more distal gut segments
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