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On alcohol dose-response curve test days rats received either 0.51.0 g/kg alcohol, followed by the standard 20-minute delay, and 2-minute test session, then an additional 1.5 g/kg alcohol and a second 20-minute delay and test, yielding cumulative doses of 2.02.5 g/kg
However, these agents are associated with increased thyroid cancer risk, and the packaging for these medications in the United States has a boxed warning stating that they are contraindicated in people with a personal or family history of medullary thyroid cancer and in patients with a diagnosis of multiple endocrine neoplasia syndrome type 2
Rogers RC, Hermann GE
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