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J Pharmacol Sci
While promoting blood vessel formation aids healing, theoretical considerations exist regarding use in individuals with active cancer or vascular abnormalities
Bei schwerer Niereninsuffizienz, unbehandelten Herz-Kreislauf-Erkrankungen oder unklarer maligner Vorgeschichte ist die Anwendung nicht empfohlen
Potential concerns and unknowns Several important unknowns remain regarding 5-amino-1mq safety
Here, we demonstrate that dihexa binds with high affinity to hepatocyte growth factor (HGF) and both dihexa and its parent compound Norleucine 1-AngIV (Nle1- AngIV) induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF- dependent cell scattering
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