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Increasing your physical activity

This may result from improved metabolic regulation due to DPP-4 inhibition, reduced glucagon levels, and enhanced insulin activity

CJC-1295 + Ipamorelin and Sermorelin are the most frequently prescribed options here, because both restore the growth hormone pulses that decline in tandem with estrogen, partially offsetting the compounding hormonal shift that drives vasomotor symptoms

Studies on rodents have shown that compounds modulating the KYN pathway have antidepressant effects (Zhu et al

2018, doi: 10.1016/j.molmet.2018.09.009 Frayling et al., A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood Pressure, Cell Rep., vol