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They work especially well when combined with GLP-1 medications

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GLP-1R side chains within 3 of Ex4-d-Ala are shown as cyan sticks

To generate pCFJ150-lag-2p::rde-1::P2A::mKate2 , lag-2 promoter of 2982 bp was amplified from pJK590, rde-1 from pCF1020, and P2A::mKate2 from TC690