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Type 1 contains vildagliptin and saxagliptin, which bind only to the S1 and S2 subsites and form a covalent bond with the nitrile group of their cyanopyrrolidine moiety and Ser630 of DPP-4
however, the study did not include an untreated control group of patients with ALS [19]
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It's important to note that these capsules may interact with certain medications, including anticoagulants, anticonvulsants, antibiotics, anti-inflammatory drugs, and chemotherapy agents
With advances in drug development, these peptides are modified to enhance their stability and efficacy, such as extending their half-life or improving their resistance to enzymatic degradation
