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Folic acid should be used with extreme caution in patients with undiagnosed anemia
Short-term GHK-Cu use (weeks to few months) typically shows benefits gradually declining toward baseline over 2-4 months post-discontinuation as newly synthesized collagen undergoes normal degradation without replacement at treatment-stimulated rates
Improves sleep architecture without sedation or dependency
Topical GHK-Cu is usually well tolerated, but some patients may notice mild irritation or redness, especially after procedures or with strong actives
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