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However, the analgesic effects of liraglutide were not observed in GSK3 (S9A) mice, indicating that liraglutide relieved diabetic pain by suppressing the NLRP3 inflammasome in microglia through GSK3 [84]
Its part of a class of drugs called GLP-1 receptor agonists
Importantly, AOD9604 achieved these effects without activating the growth-promoting pathways that full-length growth hormone uses, which is why it doesnt cause the unwanted side effects of growth hormone therapy such as insulin resistance or abnormal growth
10.1111/1348-0421.12175 75 NishidaA.NishinoK.OhnoM.SakaiK.OwakiY.NodaY.et al (2022)
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