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Intlekofer KA, Petersen SL

If hypoglycemia occurs, follow the American Diabetes Association's recommendation to treat with 15 grams of fast-acting carbohydrate, wait 15 minutes, and recheck blood glucose (the "15-15 rule")

in the gut and brain, it slows gastric emptying and reduces appetite

Freezing a liquid solution creates ice crystals that can act like microscopic knives, destroying the peptide's structure

These in vitro mechanisms were recapitulated ex vivo, as observed by the strong correlations of ex vivo 15LO1 protein with intracellular GSH ( r = 0.68, P = 0.005) and GSH:GSSG ( r = 0.62, P = 0.014) in freshly brushed HAECs (Figure 3F)