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These medications, which include Novo Nordisk's semaglutide, sold as Ozempic and Wegovy, and Eli Lilly's tirzepatide, sold as Zepbound and Mounjaro, are not recommended for use during pregnancy because their safety for the fetus is unknown and animal studies have suggested potential risks

demonstrated that GLP-1 RAs could alleviate cytoplasmic Ca 2+ overload in VSMCs in SHRs, improve the arterioles systolic and diastolic functions, and reduce BPV by upregulating Na + /Ca 2+ exchanger 1 (NCX1) expression via the Akt signaling pathway [80]

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The whole transcriptome sequencing of both early-stage and late-stage CRC tissues highlighted key lncRNAs associated with CRC (109)