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For years, the options have been frustratingly limited: rest, physical therapy that feels endless, injections that offer temporary relief, and surgery as a daunting last resort

Preclinical studies in rodents with long-acting GIP, GLP-1, and GLP-2 analogues, alongside related clinical trials, suggest these molecules are safe, and furthermore, may improve overall bone health

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Titration involves starting at a very low dose and gradually increasing it over several months

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