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The study also demonstrated that GLP-1 is not detectable in cerebrospinal fluid (CSF) during this period, suggesting that it did not enter the brain via the bloodCSF barrier but likely through direct passage across the BBB [16]
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An agonist is a molecule that activates the receptor
The scoring standard for IHC staining adopted the immunoreactive score (IRS) system [15, 16], with the specific rules as follows: the staining intensity of GGCT protein was classified into four grades, where a score of 0 indicated no staining signal, 1 indicated weak positivity, 2 indicated moderate positivity, and 3 indicated strong positivity
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