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These substances clog your arteries over time, forming hard plaque that makes it harder for blood from your heart to flow through your blood vessels

The image above is a sketch of the system

Furthermore, in a study done to investigate the roles of PPIs and SIBO and their effects on bile acid metabolism, patients taking PPI medication and having SIBO induced a reverse ratio of conjugated and unconjugated bile salts (1:3) when compared to patients using PPIs without SIBO (3:1) (Theisen 2000)

This, in turn, can compromise the structural and functional integrity of the cells nucleic acids, proteins and lipids [4]

This is by design