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Comparison groups included 85,015 pairs, and each GLP-1 starter was paired with 1 DPP-4 starter of similar age, sex, race, weight, laboratory values, year of prescription and medical history

Int J Mol Sci 24:2513

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The build-up of ROS induces ER stress, causing the release of damage-associated molecular patterns (DAMPs) like calreticulin, ATP and high mobility group box 1 [261, 262]