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Conclusions: Cere treatment was well tolerated and resulted in significant improvements in the global score two months after the end of active treatment

All the reported resolutions were based on the gold standard FSC 0.143 criterion in Supplementary Fig

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IGF-1 receptor as the restriction point of the cell cycle

16 Transfer of these vesicles to previously untreated recipient tubular cells induces a canonical ferroptotic phenotype, including loss of GPX4, accumulation of lipid ROS, increased malondialdehyde levels, and progressive membrane damage