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In a rat moderate contusive SCI model, subcutaneous administration of exenatide immediately post-injury and again at 7 days significantly improved hindlimb motor function without inducing hypoglycemia [66]
Postpartum weight retention that resolves gradually with lifestyle changes may not warrant medication
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The lack of immunogenicity has practical implications: the peptide can be used for extended periods without loss of efficacy due to antibody neutralization, there is minimal risk of allergic or hypersensitivity reactions, and repeated treatment cycles are supported as prior exposure does not sensitize the immune system
Scientific and clinical sources emphasize that preserving muscle, supporting recovery with adequate sleep, and avoiding overly aggressive calorie deficits can help maintain energy and physical function
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