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[8] Those data are important for target biology in neuropathic-pain systems, but they do not establish LanCL1 as the mediator of adipocyte lipolysis, fat oxidation, or body-weight effects

Instead, it reduces the underlying causes of pain: inflammation, tissue damage, and impaired blood flow

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Hua S, Marks E, Schneider JJ, Keely S (2015) Advances in oral nano-delivery systems for colon targeted drug delivery in inflammatory bowel disease, selective targeting to diseased versus healthy tissue

Matrigel tube formation was studied using cells pretreated with specific MAPK inhibitors