Despite its advantages, its important to acknowledge GHK-Cus limitations when compared to traditional acne treatments in a research context: Limited Direct Evidence for Active Acne Vulgaris: While it has anti-inflammatory properties, there is currently limited direct clinical evidence specifically demonstrating GHK-Cu as a primary treatment for active acne breakouts (e.g., reducing papules, pustules, or cysts)
Known hypersensitivity to peptide components
W., Lee, H., Moon, S., & Chang, I
available in PMC 2010 Jun 23
Skeletal muscle expansion occurs through IGF-1 and testosterone pathways, which the peptide does not stimulate significantly