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Many individuals on these medications find that they eat less, but often what they do consume can be low in essential nutrients, particularly protein

Obesity: A medical condition characterized by an excessively high body mass index (BMI), often linked to health risks like diabetes and heart disease

Lipoprotein(a): a genetically determined, causal, and prevalent risk factor for atherosclerotic cardiovascular disease: a scientific statement from the American Heart Association

For example, although vagal afferents were once thought to be fairly homogenous in their signaling capacity and function, extensive tracing and single-cell sequencing studies have demonstrated their complexity and diversity 28,31,32

it required deliberate medicinal chemistry to shift binding affinity by 50-fold