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Higher-Caution Situations Extra medical supervision is important if you: have a history of reactions to injectable vitamins/cobalamins have significant kidney or liver disease are pregnant or breastfeeding are offered a compounded MIC B12 product without clear labeling of ingredients, concentrations, and compounding source The FDAs overview of compounding helps explain why quality can vary (see Compounding and the FDA: Questions and Answers )
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Keatings lab is also designing peptides that could interfere with other relatives of Mcl-1, including one called Bfl-1, which has been less studied than the other members of the family but is also involved in blocking apoptosis
Precautions General Doses of vitamin B12 exceeding 10 mcg daily may produce a hematologic response in patients who have a folate deficiency
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