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Such an approach helps mitigate the risks associated with improper use, such as starting at higher-than-recommended doses or making frequent, unsupervised adjustments to dosing schedules
where S is the substrate (GSH), v is the reaction rate, k1 is the apparent first-order rate constant k1 was calculated based on the slope of fitted v -[ S ] curve
doi:10.1002/prp2.962 163
Curtis, M
Baseline serum creatinine and estimated glomerular filtration rate should be documented, with repeat testing if patients experience significant vomiting or diarrhea
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