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Y., Yazici, D., Pizzagalli, D

This can lead to symptoms such as: Stomach pain or discomfort Heartburn or indigestion Nausea In severe cases, ulcers or gastrointestinal bleeding People who take ibuprofen frequently or in high doses, have a history of stomach ulcers, or are older adults are at higher risk of experiencing stomach pain or more serious complications

The buttocks contain sufficient subcutaneous fat in most patients, making intramuscular injection unlikely when using standard needle gauge (27-29G) at the correct depth of approximately one-half inch

Others sail through four weeks without a single symptom, only to get blindsided when the dose goes up

Ultimately, the decision comes down to individual patient response, treatment goals, and any underlying health conditions