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Since GLP-1 medications already slow digestion, these compounds amplify discomfort significantly

Regarding medication management, for patients with clinical cardiovascular disease, a sodiumglucose cotransporter-2 (SGLT2) inhibitor or a glucagon-like peptide-1 (GLP-1) receptor agonist with proven cardiovascular benefit is recommended

This article was researched against primary regulatory, trial, prescribing, and manufacturer sources where available

Patients should be monitored for treatment response through serial measurements of weight, waist circumference, glycemic parameters, and lipid profiles

Markham A, Keam SJ