We want to kind of understand who these drugs are for and what we know about how they're working
Semaglutide, tirzepatide, and retatrutide (Biosynth, Compton, UK, lot #s 0000042482, 0000054911, and 0000205204 respectively) were dissolved in 0.3% phosphate-buffered saline (PBS), which was adjusted to a pH of 8.0 using NaOH and injected subcutaneously (s.c.) at 1 ml/kg
Ozempic PI
Retatrutide titration schedule in the combination The retatrutide titration in a combination protocol follows the same fundamental escalation pattern as monotherapy, but with two important modifications
Serious side effects, including potential kidney failure and pancreatitis, are associated with tirzepatide use, necessitating careful monitoring