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Still, larger studies, including patients from other parts of the world and a longer treatment period, are needed to validate methylcobalamins therapeutic effects in this subset of ALS patients, the authors noted.

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In support, recently BPC 157 increased the survival rate of cultured enteric neurons and the proliferation rate of cultured enteric glial cells (Wang et al., 2019)

Rare hypersensitivity reactions , including cobalt allergy (as cobalamin contains cobalt), have been documented