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Retatrutide is a triple-receptor agonist peptide that targets: GLP-1 (appetite regulation) GIP (metabolic signaling) Glucagon receptor (energy expenditure) This combination makes it a next-generation metabolic therapy currently being studied for weight loss and metabolic optimization
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Weeks 9-12 (4mg): the inflection point Four milligrams is where retatrutide distinguishes itself from lower-dose GLP-1 agonists
Hepatology 68 , 2A (2018)
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