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Conclusions These findings hold promise for the development of effective weight loss interventions in this population group

In practice, stacking multiplies uncertainty: more compounds more chances of impurity/contamination more pathways affected more interaction risk more variables harder to know what helped (or harmed) If you take only one clinical principle from this article: the more experimental the stack, the more conservative your risk posture should be

PMID: 24080471 Chen Y, et al

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