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In the liver, it diminishes glucose production by blocking gluconeogenic enzymes, which are essential proteins in glucose synthesis (Ahrn 2015
Shared decision-making, informed by clinical evidence and patient values, is essential to optimise outcomes and adherence
GLP-1Rs are expressed on eosinophils and neutrophils, and GLP-1RAs can attenuate eosinophil activation and LPS-induced expression of pro-inflammatory cytokines, including IL-1, IL-1, IL-6, TNF- and IFN- (23,149,150)
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