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In addition, GLP-1RAs can effectively upregulate the expression of myogenic regulatory factors MyoD and MyoG, while inhibiting the transcription of key ubiquitin-ligases MAFbx and MuRF1 in muscle atrophy
Retrieved December 5, 2014
Loss of GLP-2R action did not impact jejunal circumference or crypt depth (Supplementary Data 1), however, it significantly blunted the increase in jejunal villi length observed with cold stress compared to WT controls (Fig
- Tolerability profile consistent with the incretin class, with gastrointestinal events most commonly reported in studies (e.g., nausea, diarrhoea, and constipation)
M.KelleherJ.WoodD
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