In the ATTAIN-2 trial (participants with obesity and type 2 diabetes), GI adverse event rates were somewhat higher than in ATTAIN-1: nausea 20.1-36.4% versus 8.4% with placebo, vomiting 12.8-23.1% versus 3.8%, diarrhea 21.3-27.4% versus 15.0%, and constipation 17.7-22.4% versus 7.8%
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Gilteritinib, a highly potent FLT3 inhibitor, has demonstrated promising clinical outcomes in adults with relapsed/refractory (R/R) FLT3-mutated AML [111]
No NAFLD patient had clinical evidence of hepatic decompensation, such as hepatic encephalopathy, ascites, variceal bleeding, or a serum bilirubin level greater than twice the upper limit of normal
Lymph node fibroblastic reticular cells in health and disease