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2 2) Modulation of the nitric-oxide (NO) system & vascular tone Ex vivo aorta studies show BPC-157 modulates vasomotor tone in an NO-dependent manner, likely via SrcCav-1eNOS interactions that increase NO generation

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The combination is synergistic because BPC-157 and TB-500 address complementary stages of the healing cascade: Phase 1, Inflammation (Days 1-5): TB-500 suppresses the inflammatory cytokine response while BPC-157 begins upregulating growth factor signaling at the injury site

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