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A B12 shot is a quick intramuscular injection of vitamin B12 (cobalamin) that bypasses the stomach acid, liver metabolism, and intestinal absorption issues that limit oral B12 to roughly 1% bioavailability in most adults

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The reason we say this is a marketing scheme rather than accurate promises is because: The research findings only apply to animal models and no studies demonstrating efficacy in human models

for the related NAD+ research, see NAD+ and Sirtuins

Matter 3 , 18451861 (2020)