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The depletion of acetylcholine not only causes devastating cognitive brain fog but also contributes to the rapid heart rate, digestive motility issues, and temperature dysregulation that make dysautonomia so debilitating
There is no universal rule
IM up to 3/week provides less frequent, moderate dosing
Furthermore, rapamycin-treated CAR T cells had significantly higher in vivo expansion, with absolute CAR+ cell counts in the peripheral blood of mice reaching a mean of tenfold higher compared with untreated CAR T cells on day 14 post injection (Fig
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