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Photostability evaluation To test the photostability in buffer and cell culture media, PLGA nanoparticles encapsulating DDA-GSH-AuNCs in water (2 mg/mL) was mixed with water (control), PBS or DMEM that contains 10% FBS (final concentration of PLGA nanoparticles is 0.5 mg/mL and AuNCs 4 g/mL as gold)

The mechanism appears to be interference with erythropoiesis

Participants The study involved 45 healthy adults, males and females, and was conducted at the Philippine General Hospital, Manila

Statistical analyses Data were analyzed using SPSS Statistics software (IBM, Version 19) and presented as the mean standard deviation

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