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At 120 kilograms, it runs approximately 33 percent lower

Observational data from 240 patients showed no statistically significant difference in weight loss outcomes between semaglutide monotherapy and semaglutide plus Lipo B at 24 weeks (16.8% vs 17.3% mean reduction)

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In other words, semaglutide engaged Alzheimers biology but not strongly enough, or early enough, to translate into clinical benefit as a stand-alone therapy