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Retatrutide is not yet licensed by the MHRA or EMA, and published Phase 2 data have not identified depression as a significant adverse event
Interestingly, vitamin C can decrease baseline levels of lipid peroxidation (measured as malonaldehyde) while reducing GSH levels in the skin, suggesting a complex interplay of antioxidants within skin cells 172
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However, the combination does not eliminate the need for glucose monitoring during steroid therapy