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The most common are gastrointestinal issues, including nausea, which typically occurs during dose escalation, vomiting in some patients, diarrhea or constipation, and abdominal discomfort

Semaglutide is not contraindicated in inflammatory bowel disease, but patients with ulcerative colitis or Crohn's disease should discuss their condition with their healthcare provider before starting treatment

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Psychoneuroendocrinology 35 , 12031212, (2010)

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