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Mechanistically, BPC-157 appears to favor natural homeostasis of the GABA receptor complex through pathways distinct from direct GABA-A receptor agonism

Rabe 2013)

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however, GHR ablation in broader neural populations did not produce additional effects as compared to AgRP GHR KO mice, emphasizing a crucial role of AgRP neurons mediating GH responses

Clinical research has suggested that the levels of FOXO proteins in the central nervous system may be altered in research models of neurodegenerative disorders (NDDs)