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In Phase 1 detoxification, liver enzymes (primarily the cytochrome P450 family) process these toxins, often making them even more reactive and dangerous in the short term

No published clinical trial has shown a connection between glutathione supplementation and increased body weight or fat accumulation

Wechsler, Shamsah Kazani, and Gautham Marigowda

However, it should be noted that studies of the protective effects of DHODH have recently come under severe criticism based on experimental data (Mishima et al., 2023)