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Previous studies have reported that GPX4 genetic deficiency leads to nephrotoxic effects [19], and its role in ischemia/reperfusion-induced acute kidney injury and obstructive renal fibrosis is well-documented [14, 38]

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In addition, dimorphic fungi such as Benjaminiella poitrasii , Mucor racemosus , and Schizophyllum commune have been reported to possess different NAD + - and NADPH-glutamate dehydrogenase activities when growing in the yeast and filamentous forms 14,15,16

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