Cytokine Modulation Pro-inflammatory cytokines like TNF-alpha, IL-6, and IL-1beta drive the inflammatory cascade that causes pain, swelling, and tissue damage
One trial found that both pregabalin and duloxetine improved patient-reported CIPN symptoms, with 150 mg of pregabalin performing better than 60 mg of duloxetine (Salehifar 2020)
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Side Effects can be swelling, redness, tingling or numbness, drainage at the injection site, prolonged bleeding, and possibly some pain at the injection site
Others simply don't respond well to copper peptides and should explore alternatives