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Though exact dosing for retatrutide in the weight-loss setting is still being defined (because many of the uses remain investigational), in the key trial adults with obesity treated weekly showed large body weight reductions: e.g., up to ~17.5% at 24 weeks and up to ~24% at 48 weeks in certain dose groups

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3.4 Post-traumatic stress disorder (PTSD) Gut microbiota alterations in PTSD are increasingly evident in human cohorts, with consistent depletion of SCFA-producing taxa and enrichment of inflammatory pathobionts, while taxa level signatures vary across geography and trauma type (Ke et al., 2023

Oligomerization of a glucagon-like peptide-1 analog: bridging experiment and simulations