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(STEP-1 trial)

Therapeutic efficacy of voltage-gated sodium channel inhibitors in epilepsy

Although there were no statistically significant differences in DFS and OS between the radiotherapy and ALND groups over a ten-year follow-up, the primary endpoint, the 5-year axillary recurrence rate, was significantly higher in the SLNB group compared to the ALND group, failing to meet the predefined non-inferiority margin

In addition to weight loss, the trial also assessed how much retatrutide reduced pain from knee osteoarthritis using a 20-point scale known as the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), with higher scores indicating more severe pain

Kayumov, Kazan Federal University, Russia Updates Copyright 2019 Das, Paino, Manoharan, Farrell, Whiteley, Kriel, Glasbey and Manos