Further investigation is needed regarding the regulation of the GCH1-BH4 antioxidant pathway by PTMs
(National Library of Medicine) Many discontinue due to side effects or affordability, reducing the drugs effectiveness further
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2a, b) highlights the importance of the bioavailability of cysteine to enable cells to adapt to metabolically challenging conditions, as well as mediating cancer cell survival, tumour growth, metastases formation, resistance to therapy and disease recurrence