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Chronologically at age 60 the frequency of AD is approximately 1%, at 65 years 10 %, at 85 years 30% and is now the sixth leading cause of death in the U.S
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Adipocyte-specific deficiency of Janus kinase (JAK) 2 in mice impairs lipolysis and increases body weight, and leads to insulin resistance with ageing
PMID: 34445382
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