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Hepatic vagotomized and sham-operated mice were recovered under chow (CE-2) diet for 1 week before experiments

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As no pregnancy or lactation data exist for retatrutide, women who are breastfeeding should not use it

Importantly, the liver benefits appear not to be solely explained by weight loss, suggesting an independent therapeutic impact on liver health

Because copper plays a key role in enzymatic activity and redox biology, GHK-Cu is also examined as a carrier system for delivering copper ions in a biologically accessible form