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The overexpression of circ_0000250 in ADSC-EVs results in enhanced healing in diabetic mice through the induction of autophagy mediated by the miR-128-3p/SIRT1 axis since epidermal SIRT1 is responsible for the modulation of inflammation, wound healing and cell migration [120]
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Spicer J, Shewale J, Antonoff M, Correa A, Hofstetter W, Rice D, Vaporciyan A, Mehran R, Walsh G, Roth J, Swisher S , Sepesi B
PMID: 17426848